Polycystic ovary syndrome (PCOS) is a complex and distressing life-long condition. It is the commonest endocrine disorder among women of reproductive age, affecting 5-15% of women. PCOS causes short-term effects due to hormonal imbalance as well as longterm effects relating to underlying insulin resistance and consequent hyperinsulinaemia, a form of metabolic syndrome. How can we achieve effective reduction of risk factors in these women to prevent premature cardiovascular disease?